Abstract

Vasculitis is a spectrum of collagen diseases of multifactorial etiology, associated with inflammation of the vessel wall, this inflammation is potentially fatal if not treated in an adequate time and has a great potential of complications to generate morbidity in the patient who suffers it. In this particular case, Wegener’s granulomatosis (associated with ancas antibodies), also known as granulomatosis with polyangiitis, was addressed. The only risk factor recognized was the presence of multiple respiratory infections without successful treatment, which, added to a proximal clinical presentation of endotracheal tube bleeding, would indicate a vasculitis, which would be confirmed by the presence of ancas antibodies. The management consisted in the administration of plasmapheresis cycles and immunomodulatory scheme, however, given the advanced clinical picture and multisystemic involvement of the patient, the outcome was lethal.

Keywords: Granulomatosis with Polyangiitis; Wegener’s Granulomatosis; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Vascular Diseases; Vasculitis.