<span name="style_bold">Anti-fungi activity of organic extracts from the tree <span name="style_italic">Fagara monophylla</span> (Rutaceae) in Venezuela.</span> The tree <span name="style_italic">Fagara monophylla</span> (Rutaceae) in Venezuela.<span name="style_italic">Fagara monophylla</span> ranges throughout Tropical America. The genus <span name="style_italic">Fagara</span> has a diversity of alkaloid compounds with antibiotic properties; nevertheless, there are few reports antifungal activity of its organic compounds. Organic extracts from Venezuelan <span name="style_italic">F. monophylla</span> were tested for antimicrobial activity against <span name="style_italic">Aspergillus terreus</span>, <span name="style_italic">A. flavus</span>, <span name="style_italic">Penicillium digitatum</span>, <span name="style_italic">P. funiculosum</span>, <span name="style_italic">P. citrinum</span>, <span name="style_italic">Paecilomyces</span> and <span name="style_italic">Candida albicans</span>. Minimal Inhibitory Concentration (MIC) was determined. The susceptibility trials of organic fractions (Hex., CH<span name="style_sub">2</span>Cl<span name="style_sub">2</span> and MeOH) showed that the highest inhibition was presented by MeOH against <span name="style_italic">A. flavus</span> (55 mm), <span name="style_italic">P. digitatum</span> (60 mm), <span name="style_italic">P. funiculosum</span> (56 mm) and <span name="style_italic">C. albicans</span> (26 mm). The activities of MeOH/EtOAc fractions 1 and 2 suggest a combined effect against <span name="style_italic">A. flavus</span>, <span name="style_italic">P. digitatum</span> and <span name="style_italic">P. funiculosum</span>. The MIC of 1 MeOH/ EtOAc subfraction activity was lower against C. albicans (32 µg/ml) and moderate (128 µg/ml) against <span name="style_italic">P. digitatum</span>. This organic extract has a great antifungal potential. The phytochemical proves and TLC testing on the organic extract, and the MeOH/EtOAc subfraction, respectively, indicated the presence of alkaloid compounds. Rev. Biol. Trop. 55 (3-4): 767-775. Epub 2007 December, 28.. This organic extract has a great antifungal potential. The phytochemical proves and TLC testing on the organic extract, and the MeOH/EtOAc subfraction, respectively, indicated the presence of alkaloid compounds. Rev. Biol. Trop. 55 (3-4): 767-775. Epub 2007 December, 28.

actividad antifúngica; Fagara monophylla; hongos; MIC; extracto orgánico