Open-access Acute myocardial infarction without obstructive coronary lesions in a patient with Graves’ Basedow disease

Abstract

The myocardial infarction with non-obstructive coronary arteries is defined as an acute myocardial infarction without angiographically obstructive coronary artery disease or stenosis ≤ 50%. From a pathophysiological point of view, it was associated with rupture of small atherosclerotic plaques, coronary dissection, vasospasm, embolism, muscle bridges, imbalance in myocardial oxygen supply-demand, microvascular dysfunction, among others. We present the case of a 42-year-old female patient diagnosed with acute coronary syndrome with anterolateral ST segment elevation whose coronary angiography reported severe vasospasm without obstructive coronary lesions associated with Graves’ disease and hyperthyroidism diagnosed during hospitalization based on her history, clinical presentation and thyroid function tests. She started treatment and after 6 weeks was euthyroid without cardiovascular events.

Keywords: MINOCA; Vasospasm; Graves Basedow; Hyperthyroidism.

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Colegio de Médicos y Cirujanos de Costa Rica Apdo. 548-1000, Sabana Sur, San José, Costa Rica, San José, San José, CR, 504-1000, 2210-2200, 22102279 - E-mail: actamedica@medicos.cr
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